Ethylene oxide (EtO) is a flammable, colorless gas used as an agent to sterilize equipment and plastic devices that cannot be sterilized by steam, such as healthcare devices and instruments. Ethylene oxide is also used to make other chemicals that produce many everyday products including plastics, textiles, adhesives, detergents and cosmetics.
Hospital equipment sterilization facilities are among those sources that use ethylene oxide (EtO) for sterilization which is recognized as the best practice by the medical industry. With no suitable alternative available at this time, controlling exposure through air pollution control is necessary as the U.S. EPA has identified ethylene oxide as a hazardous air pollutants (HAPs).
In 2016, the U.S. Environmental Protection Agency (US EPA) updated the risk profile for EtO, significantly reducing the acceptable exposure level. In August 2018, the US EPA further announced that “Latest National Air Toxics Assessment Shows Potential Long-Term Health Concerns in Some Areas” and is taking steps to address emissions from some industrial facilities across the country. The NESHAP for sterilization facilities has not yet been changed.
More information on the EPA findings can be found here:
Medical Equipment Sterilization
Bulk sterilization is the most common process, where products to be sterilized are placed in a sterilization vacuum chamber and are exposed to a sterilant gas such as EtO at a predetermined temperature, humidity level, and pressure. Following their removal from the sterilization chamber, the sterile products are place in an aeration room (to allow further diffusion of residual EtO) and kept there for several hours or days depending on the product.
Ethylene oxide (EtO) is an alkylating agent that disrupts the DNA of microorganisms, which prevents them from reproducing. The EtO penetrates the breathable packaging and sterilizes all accessible surfaces of the product to render products sterile by alkylation of proteins essential for cell reproduction.
Catalytic oxidizers and scrubbers are the most widely accepted control technologies available to control VOC emissions from the EtO sterilization processes.
Catalytic oxidation of volatile organic compounds (VOCs), including ethylene oxide, works by reacting the harmful air pollutants over a specially designed catalyst where VOCs are converted to CO2, water vapor (H2O), and usable heat. These harmless byproducts are passed through a heat exchanger where the gas stream energy is transferred to the incoming exhaust. Catalytic oxidation can provide a minimum +99% VOC destruction even at the lowest flow and solvent loadings. Because catalytic oxidation is applicable to the control of lower EO concentrations, facilities can manifold several EO emission sources to one control device. In some situations, low-concentration emission sources can provide part or all of the necessary diluent air.
Scrubbers are aqueous systems used to absorb EtO vent gas and are also designed for very high efficiency of EtO removal. EtO is extremely water soluble, so vent gas is typically fed to a scrubber column filled with random packing and the EtO is absorbed by an aqueous stream running countercurrent to the vent gas to complete the hydrolysis of the EtO. Once the concentration of ethylene glycol reaches a predetermined weight percentage, the efficiency of the scrubber declines requiring process downtime as the scrubber liquid needs to be replaced and properly disposed of leading to additional ongoing operating costs.
Founded in 1969, Catalytic Products International (CPI) is a leader in enabling clean production through the implementation of air pollution control systems for VOC, HAP, and Odor related issues. CPI has extensive experience installing Catalytic Oxidizers (CatOx) at multiple U.S. and global ethylene oxide sterilization facilities for the abatement of ethylene oxide (EtO) emissions.